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Probiotic · in-depth review

Saccharomyces boulardii

Saccharomyces boulardii

Saccharomyces boulardii is a yeast whose cell wall is not destroyed by commonly used antibacterials. It secretes proteases that break down bacterial toxins, used for acute and antibiotic-associated diarrhea.

Also known asS. boulardii
Related symptomsDiarrhoeaBloating

Marked asPrimarySupporting

Primary

Shorten antibiotic-associated diarrhea

As a yeast, its cell wall and metabolism are not destroyed by commonly used antibacterials, so it can persist in the gut lumen during an antimicrobial course, adsorb pathogens, and stimulate mucin. What is felt usually sits on fewer watery stools and less tenesmus; before the course ends, the lumen still needs this fungal barrier holding.

Primary

Shorten acute watery diarrhea

Saccharomyces boulardii releases proteases that directly degrade some bacterial toxins and reduce the intestinal epithelium's response to toxin. Antibiotic-associated diarrhea, traveler's diarrhea, and C. difficile-related discomfort are the most studied settings; watery-stool counts often rise or fall within days.

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With foodDepending on the product form, it may be taken with food or after a meal
Best timeMorning or midday, mainly
SolubilityInsoluble, Water-dispersible

After continued use, reassess by how you feel and whether you still need it.

General wellnessTypical daily intake for general wellness is often 250–500 mg (about 5–10 billion CFU)
Specific needsTypical adult daily safety upper limit is about 1,000 mg (about 20 billion CFU); even for acute use, do not exceed this on your own long term, and check the strain/CNCM ID.

How oftenUsually fine to use daily; adjust to personal need.

Cautions

Strains are not interchangeable; immunocompromised, critically ill, pregnant, or medicated people should ask a clinician first.

Interactions

  1. Immunosuppression, central lines, or critical illness (bacteremia risk)
  2. 活動性胰臟炎須問醫生
  3. Antifungals (may cancel Saccharomyces boulardii)
Common side effects

· Some people may notice mild digestive or other discomfort.

Rare but important

· If discomfort persists or you worry about drug interactions, seek professional advice.

Long-term dependenceNo typical addiction evidence; do not exceed labeled amounts on your own long term.

Sources

These are institution pages you can check—not a certification of this ingredient.

Medical disclaimerThis page is compiled by the HerbBB editorial team for general health information only. It is not a substitute for advice from a doctor, pharmacist, or other qualified clinician. If you have a health condition, take medicines, or are pregnant or breastfeeding, speak with a professional first.