ADVERTISEMENT

Vitamin · in-depth review

Vitamin B5 (Pantothenic Acid)

Vitamin B5 (Pantothenic Acid)

Pantothenic acid is a structural piece of coenzyme A. Fatty-acid synthesis and β-oxidation both need it to start. Almost all foods contain it, so true dietary deficiency is rare.

Also known asPantothenic AcidPantothenate
Health goalsDaytime Fatigue
Related symptomsFatigue

Marked asPrimarySupporting

Primary

Promotes fatty-acid oxidation

Pantothenic acid is phosphorylated and joined to cysteamine to build coenzyme A, so fatty acids can be activated and enter β-oxidation. Whole grains, eggs, mushrooms, and animal liver all contain it; sources are wide, and a balanced diet usually already meets the need. People who truly need a supplement are mostly those with extreme picky eating or very poor absorption.

Primary

Supports fatty-acid synthesis

The acyl-carrier protein on fatty-acid synthase likewise contains a pantothenate residue so the carbon chain can be lengthened one unit at a time. That explains why B5 takes part in both breaking fat for energy and making fatty acids; rapid turnover of scalp and mucosa also relies on this acyl path to attach the raw materials.

ADVERTISEMENT

Fatigue

Pantothenic acid is phosphorylated and joined to cysteamine to build coenzyme A, so fatty acids can be activated and enter β-oxidation. People who cannot get going by day and feel foggy in the afternoon more often notice stamina for tasks and mental freshness after several continuous weeks.

With foodMay be taken on an empty stomach or with food; if it bothers you, switch to after a meal
Best timeMorning or midday
SolubilityWater-soluble

A generally balanced diet usually provides enough pantothenic acid.

General wellnessAdults 5 mg/day (AI)
Specific needsNo official UL; typical adult supplement daily safety upper limit is about 1,000 mg, and do not exceed this on your own long term.

How oftenCan be used at the adequate daily intake.

Cautions

Very high supplemental doses may upset the stomach; routine self-use is unnecessary.

Interactions

  1. Public monographs do not list a clear drug conflict; people on medicines should still ask a clinician first
Common side effects

· Large doses may cause diarrhea or stomach upset

Rare but important

Still being compiled

Long-term dependenceDoes not cause addiction or typical tolerance.

Sources

These are institution pages you can check—not a certification of this ingredient.

Medical disclaimerThis page is compiled by the HerbBB editorial team for general health information only. It is not a substitute for advice from a doctor, pharmacist, or other qualified clinician. If you have a health condition, take medicines, or are pregnant or breastfeeding, speak with a professional first.