ADVERTISEMENT

Postbiotics · Polyphenol metabolites

Urolithin A

Urolithin A

Urolithin A is a dibenzopyranone metabolite made when specific gut bacteria convert ellagitannins from pomegranate and berries, used to start mitophagy and support muscle endurance.

Also known asUA
Related diseasesSarcopenia
Related symptomsFatigueMuscle soreness

Marked asPrimarySupporting

Primary

Promotes mitochondrial autophagy

Urolithin A can induce recycling of damaged mitochondria, so cellular-respiration markers more often improve in trials. People who get breathless on stairs after midlife or recover more slowly from training more often notice endurance and fatigue recovery after several continuous weeks.

Primary

Improves muscle endurance

The same mitochondrial-quality path lands in skeletal muscle; walking distance and repeated-contraction fatigue are often recorded in human trials. People whose everyday walking does not last as it used to, or whose legs sink quickly, more often notice easier walking after several continuous weeks.

ADVERTISEMENT
With foodTake with meals
Best timeMorning or midday
SolubilityWater-dispersible

After several weeks of continued use, reassess how you feel and how well you tolerate it.

General wellnessTypical daily intake for general wellness: urolithin A often 500 mg
Specific needsTypical adult daily safety upper limit is about 1,000 mg; if pregnant or on medicines, ask a clinician first, and do not exceed this on your own long term.

How oftenGenerally use daily as directed on the product label.

Cautions

If you are pregnant, breastfeeding, or taking medicines, ask a clinician first. Whether diet ellagitannins convert to urolithin A depends on the microbiota.

If symptoms persist or worsen, seek medical help promptly.

Interactions

  1. Public monographs do not list a clear drug conflict; people on medicines should still ask a clinician first
Common side effects

· Mild gastrointestinal discomfort or an unfamiliar taste may occur.

Rare but important

· Some people may have allergic reactions or interactions with medicines.

Long-term dependenceNo typical addiction evidence; do not exceed labeled amounts on your own long term.

Sources

These are institution pages you can check—not a certification of this ingredient.

Medical disclaimerThis page is compiled by the HerbBB editorial team for general health information only. It is not a substitute for advice from a doctor, pharmacist, or other qualified clinician. If you have a health condition, take medicines, or are pregnant or breastfeeding, speak with a professional first.