Why supplement?
Marked asPrimarySupporting
Eases mild low mood
Aerial-part extract can affect monoamine reuptake and nerve-transmission–related signals; scale scores of mild low mood often fall in trials. People who cannot get going and feel nothing for things they usually like more often see change in mood swings after several continuous weeks.
Helps settle menopausal mood
Some trials put St. John's wort on menopausal irritability, anger, and mood swings that ride with hot flushes; plant constituents and mood scales meet here. People with waves of heat and a restless mind more often see a difference in steadier mood and more continuous sleep after several continuous weeks.
How to take it?
After 4-8 weeks of continuous use, review actual benefit and tolerance.
How oftenGenerally can be used daily and adjusted to individual response.
What to watch
Cautions
Depressive symptoms or current medicines: must ask a clinician first.
If symptoms persist or worsen, seek medical help promptly.
Interactions
- CYP3A4 / P-gp induction: oral contraceptives, immunosuppressants, some HIV and cancer medicines
- Antidepressants (serotonin-syndrome risk)
- Warfarin
- Some heart medicines and antiseizure drugs
· Mild gastrointestinal discomfort or an unfamiliar taste may occur.
· Some people may have allergic reactions or interactions with medicines.
Long-term dependenceNo typical addiction evidence; do not self-use high long-term doses just to speed results.