Soy Isoflavone

The aglycone form can bind estrogen-related receptors, so menopausal hot flashes, night sweats, and waves of heat are often milder. For people who wake suddenly hot at night or flush and feel the heart race by day, changes in hot-flash frequency and sleep continuity are more often noticeable after several weeks of continued use.

Isoflavones also map onto the balance of bone formation and resorption, so bone-turnover markers and density-related observations are recorded. For people after menopause who watch height loss or aching in the lower back, differences in bone-related labs and a steadier posture are more often noticeable over weeks to months of continued use.