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Vitamin · in-depth review

Pyridoxine Hydrochloride

Pyridoxine Hydrochloride

Pyridoxine hydrochloride is used to supplement Vitamin B6 (a common B6 salt).

Also known asNo common aliases yet
Related symptomsPMS symptomsNauseaLow mood

A common B6 salt

Pyridoxine hydrochloride is phosphorylated in the body to P5P. The use is amino-acid and neurotransmitter metabolism. The hydrochloride is the most common supplement raw material.

Amino-acid metabolism

Pyridoxine hydrochloride is a source of Vitamin B6. Pyridoxal phosphate assists transamination and neurotransmitter synthesis. This form supplies B6; long-term megadoses are a safety issue, not a benefit.

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With foodMay be taken with breakfast or lunch; if your stomach is sensitive, switch to after a meal. Fat-soluble vitamins are better with fat-containing food; water-soluble vitamins can usually be taken on an empty stomach or with food
Best timeMorning or midday

If numbness or tingling persists, stop raising the dose on your own and see a doctor.

General wellnessAdults 1.3 mg/day (ages 19–50); men 51 and older 1.7 mg/day, women 1.5 mg/day
Specific needsTreatment doses for deficiency must be set by a doctor. The adult supplement upper limit is about 100 mg/day; do not exceed it on your own for long periods.

How oftenCan be used daily, but count the total from all multivitamins.

Cautions

High long-term doses can cause peripheral neuropathy; do not exceed the product or a doctor's advice.

Ask a doctor first if you take levodopa without carbidopa.

Common side effects

· Nausea or stomach upset (high doses)

Rare but important

· Numbness or tingling in the hands or feet, or unsteady walking, may signal neurotoxicity.

Long-term dependenceNot addictive; long-term excess can cause irreversible nerve damage.

Medical disclaimerThis page is compiled by the HerbBB editorial team for general health information only. It is not a substitute for advice from a doctor, pharmacist, or other qualified clinician. If you have a health condition, take medicines, or are pregnant or breastfeeding, speak with a professional first.