Bromelain

This protease refined from pineapple stem cuts peptide bonds in the gut, so bloating and a stuck feeling in the stomach after a high-protein meal are often clearly milder. For people who often fill up on meat, whey protein, or a large meal, differences in fullness easing are easier to notice when it is used with protein meals.

Proteolysis by this pineapple-stem enzyme alters local inflammatory mediators, so some human trials watch post-exercise swelling and joint scales. For people whose legs swell right after training or whose joints tighten on stairs, changes in swelling going down and ease of movement are more often noticeable after several days of continued use.

Bromelain breaks some allergy-related proteins and shapes histamine pathways; sinus trials often watch mucus volume and nasal resistance. Pineapple stem is the source; beyond digestion and exercise swelling, people stuffed and puffy in pollen season often match gaps on this allergy-comfort path; fasting use is common in trial designs.