Generalised anxiety disorder
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Herbal polyphenols · in-depth review

Apigenin

Apigenin

Apigenin is a flavone in chamomile, celery, and parsley, used for GABA-related relaxation and sleep quality.

Also known as4,5,7-trihydroxyflavone
Health goalsAcute AnxietySystemic Micro-inflammation
Related diseasesGeneralised anxiety disorderInsomnia disorder
Related symptomsAnxiety symptoms
Disease classesMental, behavioural or neurodevelopmental disorders
01

Why supplement?

Marked asPrimarySupporting

Primary

Helps the mind relax and settle

Apigenin can act at GABA-related receptors, so daytime tightness and irritability are often easier to set down. For people whose chest tightens before meetings or whose mind will not stop at night, changes in looser shoulders and steadier mood are more often noticeable after several weeks of continued use.

Primary

Supports sleep quality

The same inhibitory signaling lands at night on subjective sleep and how refreshed you feel on waking; chamomile-source trials often record these scales. For people whose thoughts keep turning after they lie down, differences in sleep continuity and next-day alertness are more often noticeable after several weeks of continued use.

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02

Which symptoms may ease?

Anxiety symptoms

Apigenin can act at GABA-related receptors, so daytime tightness and irritability are often easier to set down. People whose minds will not quiet and whose shoulders stay raised more often notice steadier mood and the body letting go after several continuous weeks.

03

Which conditions may it support?

Generalised anxiety disorder

Apigenin can act at GABA-related receptors, so daytime tightness and irritability are often easier to set down. People who still cannot gather their worries more often notice support in scale scores and bodily tightness after several continuous weeks.

Insomnia disorder

The same inhibitory signaling lands at night on subjective sleep and how refreshed you feel on waking; chamomile-source trials often record these scales. People who long feel their thoughts get louder once in bed more often notice sleep continuity and next-day alertness after several continuous weeks.

04

How to take it?

With foodTake with meals; for relaxation, may switch to after dinner
Best timeMorning or evening, depending on use
SolubilityFat-soluble, Water-dispersible

After continued use, reassess by how you feel and whether you still need it.

General wellnessTypical daily intake for general wellness: apigenin often 50 mg
Specific needsNo official UL; typical adult supplement daily safety upper limit is about 200 mg, and do not exceed this on your own long term.

How oftenUsually fine to use daily; adjust to personal need.

05

What to watch

Cautions

If you take medicines, are pregnant, or have a chronic condition, ask a clinician before use.

Interactions

  1. Sedatives and benzodiazepines
  2. Anticoagulants
Common side effects

· Some people may notice mild digestive or other discomfort.

Rare but important

· If discomfort persists or you worry about drug interactions, seek professional advice.

Long-term dependenceNo typical addiction evidence; do not exceed labeled amounts on your own long term.

Sources

These are institution pages you can check—not a certification of this ingredient.

Medical disclaimerThis page is compiled by the HerbBB editorial team for general health information only. It is not a substitute for advice from a doctor, pharmacist, or other qualified clinician. If you have a health condition, take medicines, or are pregnant or breastfeeding, speak with a professional first.